No. of Cases Seen in a Year

  • Total Referrals: 45
  • Unilateral cleft lip and palate: 15
  • Bilateral cleft lip and palate: 15
  • Cleft palate only: 15

Treatment Funded by State for National Residents

  • Surgery costs: Part
  • Speech and Language Therapy costs: Part
  • Orthodontic costs: Part

Primary surgical protocol


Cleft Lip Repair:

  • Timing: 4-5 months
  • Type of operation: Mulliken, Delaire

Bilateral Cleft Lip Repair:

  • Timing: 5-6 mon ths
  • Type of operation: Mulliken, Millard

Cleft Palate Repair:

  • Stages: Two stage
  • 1st Stage Timing: 8 months
  • 1st Stage Type of operation: Soft Palate
  • 2nd Stage Timing: 12-18 months
  • 2nd Stage Type of operation: Hard Palate

Record collection protocol


Are records routinely collected at specific ages? No

Does this conform to WHO recommendations for different cleft types? No

Cast and photographs at birth and during pre-primary surgery orthodontics, routine orthodontic records before maxillary advancement therapy by face-mask (at age 7-8), computerized tomography before secondary bone grafting, routine ortho. records before Le Fort 1 surgery if needed.

Research

Want to particpate in research? yes

Participation in inter-centre studies? no

Current Research

Type(s) of software used: Any kind
Participation in inter-centre studies: Yes
Details of studies: Distraction Osteogenesis studies with NYU
Genetic Studies with Private Genetics Center
Various studies with other universities on Cleft.
Participation in other collaborations (projects): Yes
Details of projects: Genetic Studies with Private Genetics Center
Published research papers: Yes
Details of publications: The senior members of the team each has approximately 20 published papers.
Willing to share Powerpoint presentations: Yes

Clinical research activities interested in being involved in:

Randomised clinical trials: Yes
Inter-centre comparison of outcome: Yes
Prospective study: Yes
DNA collection: Yes





Clinical research

Clinical team members who are or would like to be involved in clinical research:
Member details: Ayşe Altuğ - Orthodontics - Associate Prof. Former Research fellow
(2000-2001) at NYU-IRPS, New York, USA

Ufuk Memikoğlu - Orthodontics - Professor

Okan Akçam - Orthodontist - Professor

Ayşegül Tüzüner - Oral and Maxillofacial Surgery - Associate Prof. Former Research Fellow QEII Health Sciences Centre Halifax, Canada

Aslı Şenol - Orthodontics - Doctorate Student

Non-clinical and laboratory research

Non-clinical and laboratory team members who are or would like to be involved in clinical research:
Member details: Ayşe Altuğ - Orthodontics - Associate Prof. Former Research fellow
(2000-2001) at NYU-IRPS, New York, USA

Ufuk Memikoğlu - Orthodontics - Professor

Okan Akçam - Orthodontist - Professor

Ayşegül Tüzüner - Oral and Maxillofacial Surgery - Associate Prof. Former Research Fellow QEII Health Sciences Centre Halifax, Canada

Aslı Şenol - Orthodontics - Doctorate Student

EU Biobank

Stored CLP DNA samples available for use in future studies:
Number for CP: We are also building up a genetic sample of various types of Cleft at the moment. We would be happy to get involved in such a DNA based study in the future.

Potential laboratory based research activities

Laboratory based research activities interested in being involved in:
Laboratory genetics/genomics research: Yes