No. of Cases Seen in a Year

  • Total Referrals: 120
  • Unilateral cleft lip and palate: 45
  • Bilateral cleft lip and palate: 20
  • Cleft palate only: 40

Treatment Funded by State for National Residents

  • Surgery costs: Part
  • Speech and Language Therapy costs: Part
  • Orthodontic costs: None

Primary surgical protocol


Cleft Lip Repair:

  • Timing: 1 - 3 months
  • Type of operation: Modified Millard and primary gingioperiostoplasty

Bilateral Cleft Lip Repair:

  • Timing: 1 - 3 months
  • Type of operation: Modified Millard and primary gingioperiostoplasty

Cleft Palate Repair:

  • Timing: 10 months
  • Type of operation: Wardill -Kilner-Veau with section of the nasal layer or in only soft palates modified Sommerlad with section of the nasal layer

Record collection protocol


Are records routinely collected at specific ages? Yes

Does this conform to WHO recommendations for different cleft types? Yes

Intercentre Collaboration Interested


Research

Want to particpate in research? yes

Participation in inter-centre studies?

Current Research

Type(s) of software used: Elaboration of web based national register
Participation in inter-centre studies: Yes
Details of studies: Plovdiv -Warshaw
Plovdiv -Lubliana
Plovdiv -Lille
Participation in other collaborations (projects): Yes
Details of projects: EUROCLEFT
EUROCRAN
Published research papers: Yes
Details of publications: List of publications – Youri Anastassov

? Dissertations

1.For the title “Doctor “ “CLINICAL AND LABORATORY STUDIES IN CHILDREN WITH CLEFT LIP AND PALATE”. Doctor Youri Anastassov.Sofia 1995 ( citated 2 times) Bulg.
2.For the title “Doctor of Science ”MULTIDISCIPLINARY MANAGEMENT OF THE FACIAL ANOMALIES Plovdiv 2008. Assistant Professor Youri Anastassov PhD

3. Rationalization -Youri Anastassov and Dinko Zahariev : Diagnostic method for children with cleft lip and palate . Certificate ? 40 17.09.1990 Sofia

4. Invention -Youri Anastassov and Dinko Zahariev : Method for determination of the age for operation in children with cleft lip and palate. Certificate for authors ? 50063 ??? ? 61 ? 6/00 Sofia 08.02. 1990

?? Books

Surgical methods in maxillofacial surgery. Under the redaction of Prof. Kavrakirov. ??.” ????” 1998 . ISNB: 954-8967-22-7
– 5. Anastassov Y. Craniofacial surgery 317-330.
– 6. Anastassov Y. Reconstructive operations in some tumors in the maxillofacial area. 485 – 505

7. The EUROCLEFT PROJECT 1996-2000.Standarts of Care for Cleft Lip and Palate in Europe. Shaw W.et coll. IOS Press.2000. ISSN:0929-6743 .Anastassov Y. Cleft lip and palate care in Bulgaria.? 32

8. Facial Anomalies. ANASTASSOV Y. POLIGRAF COMERSE 2006 ISBN-10:954-91865-1-2.

9. Progress in Medical Genetics. Publ. Date:2006, ISBN: 1-59454-489.Christo Dimitrov Shipkov, Tzanio Krastev, Youri Anastassov, Elena Dimitrova, Margarita Stefanova. Genetics and surgery of intersexual conditions. Review of the literature and our experience. CHAPTER 8.183 – 199.

10. Patologia de los labios J.L.Cedrun. –. ISBN -13:978-84-939275 editorial Ripano, Madrid 2012.
Capitulo 4. Malformaciones labiales congenitas.. Y.Anastassov,J.LCedrun, Gonzalo Landa 97-125.

??? – Publications in journals with impact factor (general impact factor 24.034) (personal impact factor 9.521) (impact factor from citations 75.45)

11. Anastassov Y., M. Ghestem, V. Martinot, P. Pellerin. Two patients with multiple facial clefts including cleft lip and palate. J. Craniofacial Surg. 4, 1993, 3: 148-152 gif -0.948 pif 0.237( citated 5 times)

12. Martinot V., S. Manouvrier Y. Anastassov, J. Ribiere , Ph. Pellerin. Orodigitofacial Syndromes Type I and II: Clinical and Surgical Studies. Cleft Palate -Cranio -facial Journal. 31, 1994, 5, 401:408. gif – 1.259 pif 0.2518 ( citated 15 times)

13. Mortier P., V.Martinot, Y.Anastassov, J.Kulik, Duhamel A., P.Pellerin. Evaluation of the results of Cleft Lip and Palate Surgical Treatment: Preliminary Report. Cleft Palate Craniofacial Journal, 43, 1997, 3:1-9. gif – 1.259 pif -0.209 (citated 9 times)

14. Anastassov Y., C. Chipkov. Analysis of the nasal deformities in cleft lip and palate patients by a new rating scale: a preliminary report. Journal of Cranio-Maxillofacial Surgery 28, Suppl. 1 2000 gif-1.926– pif-0.963( citated 9times )

15. Shipkov C, Anastassov Y. Surgical approach to conjunctival carcinoma. Br J Ophthalmol.http://bjo.bmjjournals.com/cgi/eletters/81/11/1001#4320 August 2001 gif– 2.524 pif 1.262

16.Shipkov C. Anastassov Y. Unilateral superiorly-base nasolabial island flap for the
reconstruction of the philtrum.Scand J Plast Reconstr Surg Hand Surg. 2002, 36, 3: 177-179.gif – 0.734 pif 0.363 (citated 1time )

17. Shipkov C, Anastassov Y, Uchikov A. The rubber band drain – really cheap and efficient but not so “young”. Plast Reconstr Surg.2002 Oct.110 (5)1365-6; discussion 1366 gif-2.916 pif 1.45

18. Shipkov C, Anastassov Y. Bilateral Poland anomaly: Does it exist? Am J Med Gen.2003 Apr.1;118A (1):101 gif- 2.539 pif 1.269 ( citated 4 times )

19. Shipkov CD, Anastassov YC. Orbital reconstruction after exanteration with the whole trasorbital temporalis muscle flap. Ann Plast Surg.2003 Nov.51(5)527 gif -1.499 pif -0.749 (citeted 2 times )

20. Anastasov, Y., Chipkov, C, Analysis of nasal and labial deformities in cleft lip, alveolus and palate patients by a new rating scale: preliminary report. Journal of Cranio-Maxillofacial Surgery 2003. 31, 299-3003 gif-1.926 pif 0.963 (citated 9 times )

21. Steensel, M.A.M, Shipkov C.D. , Anastassov Y.K. Poland Anatomy: Not unilateral of Bilateral
but Mosaic ( multiple letters) American Journal of Medical Genetics 2004, 125 A (2) 211-213 gif –
2.539 pif 0.846 ( citated 3 times )

22. Shipkov C; Y.Anastassov, A.Yonkov. The place of laser treatment in the management of congenital melanocytic nevi.Ann Plast Surg. 2006 Feb;56(2):222-4 gif -1.499 pif 0.499 (citated 1time)

23. Marinov Ts., Rouev P., Anastassov Y., Pellerin Ph., Kovacheva K., Jonov M., A case report of
congenital arhinia and literature review., International Journal of Pediatric Otorhinolaryngology,
2007, 238 – 242 gif -1.210 pif 0.201

24. Khater R., Atanassova P., Anastassov Y., Pellerin Ph., Martinot-Duquennoy V., Clinical and
Experimental Study of Autologous Fat Grafting After Processing by Centrufugation and Serum
Lavage, Aesth Plast Surg, 2009, 33, 37-43 . gif -1.256 pif 0.251 (citated 4 times)

?V – Publications in Bulgarian journal, citated by foreign authors

25. Shipkov H, Zheliazkov H, Anastassov Y. One-stage reconstruction of the eye
socket with vascularised temporalis muscle flap in orbital exenteration. Folia medica,
2001, 43,3:41-6 (citated 3 times)

26. Anastassov Y.,Anastassov G.,Lumerman H., Simov R. Shipkov C., Mihailov T., Traikova N.
Craniofacial fibrous dysplasia. Conservative surgical management. (Review of literature and a report
of a case) Folia Medica 2004 , 2, 56-61 (citated 2 times)

V -Publications in Bulgarian referred journals without impact factor

27. 1990, 2, 16:20.

28. 1990, 1, 1:5

29. 1990, 4, 13-17.

30.1991, 3, 10-15.

31. 1991, 3, 46:52.

32. 1991, 34, 64:70.

33. Orthodontia Quintessence 1993, 2, 27:30.

. 34.Anastassov Y., J. Ribiere, V. Martinot, Ph. Pellerin. Age osseux et dysharmonies maxillo-
mandibulaires chez les enfants porteurs de fentes labio-palatines. Rev.Stomatol.Chir.Maxillo- fac.1993,94, 5, 300-304

35. 1998, 4: 10-13.

36. Ugrinov R., C.Anastassov.,Y. Anastassov .Fibrome desmoide. Fibromatose agressive. Fibrosarcome infantile.. Actualites Odonto-Stomatologiques.1998, 201: 73-82

37.1999, 4,15-16.

38. Folia Medica 2000 .2: 280-283.

39. 9 . 2000, 5: 46-47.

40.  Poland, 2000, LVI, 2: 26-29

41. LVII, 2001, 3-4, 18-21

42.  2002, 4, 1; 12-18.

43.Dzhambazov K., Y. Anastassov, S. Andreeva, D. Beshkova, L. Epitropova, R. Simov, Y. Simova .
Incidence of middle ear effusions in cleft palate children. Pro Otology. Balkan Journal of Pathology
and Otonevrology 2002, 3, 117-120.

44. Shipkov C, R.Simov, Y.Bukov, T. Piral, Y. Anastassov. Etude anatomique du lambeau nasogénien et du lambeau du buccinateur. Applications cliniques. Annales de Chirurgie Plastique et Esthetique 2003;48:152-158 ( citated 6 times)

45. Shipkov C; Y.Anastassov, K.Djambazov, R.Simeonov, R.Simov. Nasal reconstruction with vascularized forehead flap (preliminary communication).Folia Med (Pl). 2004;46(1):22-5.

46. Khater R., Simov R., Shipkov Chr., Nikolova D., Anastassov Y., Our experience in the application of lipofilling. Folia medica (4) 2007, 46 – 51. (citated 1 time)

47. Khater R., Atanassova P., Anastassov Y., Autologous Fat Transplantation in the Facial Region – Clinical and Morphological Studies of 30 Cases, Folia Medica, L, I/2008, 29 – 34

48.  48 . 2.2009, 42- 45

49. Anastassov G,, Khater R., Anastassov Y. Correction of paralytic lagophthalmos .
Folia Medica 2011,?V

V? Publications from symposiums or congresses in full text

50. 2000  7-14.

51.  2000 15-20.

52.  2000  21-32

53. .2000. ??? 1. ???.151-154.

54. 2001.

55.Shipkov C, Anastassov Y. Reconstruction of the philtrum in bilateral cleft lip and palate with a nasolabial flap: a case report. Trans?ctions of the 9th International Congress on Cleft Palate and Related Craniofacial Anomalies in Goteborg, Sweden, June, 2001: 645–649.

56. . 2003, 97-108.

57.  21 , 20-23  2004 . 144-148.

58.  3 21 , 20-23  2004, 154-160.

59. 2005 .120-125.

60.  2005, 152-155.

61.  2005 ? 2006 ?.,  2006 ?.63 – 70.

62. .V??, ISSN 1311-9427 2005 ?

63. 2005 .129-135.

64. 2005 ? 2006 ?.,  2006 ?.71 – 77

65. , 2007 ?., 90 – 94

66.  – 25-28  2008. 262-271.

V?? Electronic publications

? 15 Shipkov C, Anastassov Y. Surgical approach to conjunctival carcinoma. Br J Ophthalmol.http://bjo.bmjjournals.com/cgi/eletters/81/11/1001#4320 August 2001 gif 2.524 pif 1.262

V??? Books for students – ? 5, ?6, ? 7

?? Scientific communications

1. Scientific communications abroad, published in abstract books

67. Anastassov Y. Les conditions preoperatoires et le developpement physique des enfants atteints de fentes labio-palatines. Journees franco-balkaniques de stomatologie. Nancy 7-8 Octobre 1991.

68. Anastassov Y. Classification of the presurgical gravity and classification of the postsurgical sresults in patients with cleft lip and palate. INTERNATIONAL PLASTIC RECONSTRUCTIVE AESTHETIC SURGERY CONGRESS. Athenes, Greece, 10-12 November 1993

69. Anastassov Y .The gingivoperiostoplasty between 3 and 5 years in cleft lip and palate patients: a preliminary study.. 1st Balkan Congress for Plastic, Reconstructive and Aesthetic Surgery. Thessaloniki 1-3 april 1999

70. Anastassov Y. Cleft lip and palate care in Bulgaria. Eurocleft INCO First European Workshop. 4rth February 1999, Manchester, UK.

71. Anastassov Y.Evaluation of the surgical results in 58 consecutive primary surgeries for cleft lip and palate I Simposio Internacional sobre las deformidades faciales congenitas. La Coruna 27-29 de Noviembre 2002

72. Koselj V.,Y. Anastassov, S.Hanstein, I.Klimova, J.Vritiskova .Complications in cleft lip and palate surgery – a five center international study. 6th Congress of Crioatian Society of Maxillofacial, Plastic and Reconstructive Head and Neck Surgery. Zagreb November 11-13.2004.
Willing to share Powerpoint presentations: Yes

Clinical research activities interested in being involved in:

Randomised clinical trials: Yes
Inter-centre comparison of outcome: Yes
Prospective study: Yes
DNA collection: Yes




Clinical research

Clinical team members who are or would like to be involved in clinical research:
Member details: Inter-center comparisons for lip-nose growth for surgery, orthodontics and growth development,
Non-clinical and laboratory research

Non-clinical and laboratory team members who are or would like to be involved in clinical research:

Member details: EUROCRAN participation 2005

Potential laboratory based research activities

Laboratory based research activities interested in being involved in:
Laboratory genetics/genomics research: Yes
Animal models research: Yes