No. of Cases Seen in a Year

  • Total Referrals: 118
  • Unilateral cleft lip and palate: 51
  • Bilateral cleft lip and palate: 12
  • Cleft palate only: 55
  • Pierre Robin Sequence: 7
  • With anomalies present: 7

Treatment Funded by State for National Residents

  • Surgery costs: All
  • Speech and Language Therapy costs: All
  • Orthodontic costs: All

Primary surgical protocol


Cleft Lip Repair:

  • Timing: 2-4 months
  • Type of operation: Millard

Bilateral Cleft Lip Repair:

  • Timing: 2-4 months
  • Type of operation: Millard, Mulliken

Cleft Palate Repair:

  • Timing: 6-9 months
  • Type of operation: V-Y Push Back –Furlow

Record collection protocol


Are records routinely collected at specific ages? Yes

Does this conform to WHO recommendations for different cleft types? No

1) Prenatal (If possible) or birth
2)1-4 Mounths
3)6-9Mounths
4)1 Year
5)1,5Years
6)2Years
7)4Years
8)5 Years
9)7-12 Years
10)13-18 Years

Research

Want to particpate in research? yes

Participation in inter-centre studies? no

Current Research

Type(s) of software used: Access
Published research papers: Yes
Details of publications: Gursu, K.G., [Classification of cleft lip and palate and their treatment]. Istanbul Univ Dishekim Fak Derg, 1969. 3(1): p. 58-69.
2. Mavili, E., et al., Three cases of oblique facial cleft: etiology, tomographic evaluation and reconstruction. Clin Dysmorphol, 1992. 1(4): p. 229-34.
3. Mavili, E., A. Kayikcioglu, and G. Gursu, Modified use of gate flap for the reconstruction of the lower lip. Eur J Surg Oncol, 1993. 19(4): p. 327-31.
4. Ozgur, F.F., O. Kocabalkan, and K.G. Gursu, Tissue expansion in median facial cleft reconstruction: a case report. Int J Oral Maxillofac Surg, 1994. 23(3): p. 137-9.
5. Kapucu, M.R., et al., The effect of cleft lip repair on maxillary morphology in patients with unilateral complete cleft lip and palate. Plast Reconstr Surg, 1996. 97(7): p. 1371-5; discussion 1376-8.
6. Mavili, E. and M. Akyurek, Use of upper lip flap for correction of nostril stenosis. Otolaryngol Head Neck Surg, 1999. 121(6): p. 840-1.
7. Ozgur, F. and D. Tuncah, Acquired clefting as a consequence of palate infection. Plast Reconstr Surg, 1999. 104(6): p. 1934.
8. Ozgur, F., D. Tuncali, and A. Kayikcioglu, Securing the nostril retainer. Plast Reconstr Surg, 1999. 104(3): p. 882.
9. Ozgur, F., D. Tuncali, and A. Kayikcioglu, Securing the nostril retainer. Plast Reconstr Surg, 1999. 103(4): p. 1328.
10. Ozgur, F. and G. Tuncbilek, Bilateral congenital pits of the upper lip. Ann Plast Surg, 2000. 45(6): p. 658-61.
11. Ozgur, F., G. Tuncbilek, and A. Cila, Evaluation of velopharyngeal insufficiency with magnetic resonance imaging and nasoendoscopy. Ann Plast Surg, 2000. 44(1): p. 8-13.
12. Tuncbilek, G., F. Ozgur, and E. Belgin, Audiologic and tympanometric findings in children with cleft lip and palate. Cleft Palate Craniofac J, 2003. 40(3): p. 304-9.
13. Marazita, M.L., et al., Genome-scan for loci involved in cleft lip with or without cleft palate in consanguineous families from Turkey. Am J Med Genet A, 2004. 126A(2): p. 111-22.
14. Ozgur, F., E. Sonmez, and G. Tuncbilek, Cleft lip and cleft palate closure in 13 month-old female with Epidermolysis Bullosa. J Craniofac Surg, 2005. 16(5): p. 843-7.
15. Tuncbilek, G., E. Konas, and F. Ozgur, A salvage procedure in cleft palate repair: suturing nasal mucosa directly to palatine process. Cleft Palate Craniofac J, 2007. 44(3): p. 233-4.
16. Ozgur, F. and H. Ozdemir, Long-term impaction of a foreign body in the hard palate. J Craniofac Surg, 2008. 19(3): p. 826-8.
17. Konas, E., et al., Congenital bony syngnathia with unilateral palatal shelf and soft palate agenesis. J Craniofac Surg, 2010. 21(5): p. 1645-7.
18. Calis, M., E. Konas, and F. Ozgur, Unusual foreign body impaction in the palate: plastic screw cap. J Craniofac Surg, 2011. 22(6): p. 2430.
19. Ozgur, F. and H.O. Kamburoglu, A Very Rare Cause of Asymmetric Velopharyngeal Incompetence: Unilateral Palate Hypoplasia. Cleft Palate Craniofac J, 2011.

Clinical research activities interested in being involved in:

Randomised clinical trials: Yes
Inter-centre comparison of outcome: Yes
Prospective study: Yes




Clinical research

Clinical team members who are or would like to be involved in clinical research:
Member details: Figen Özgür, Ersoy Konas - PRS - All

Müge Aksu - Orthodontics - All

Maviş Kayıkçı - Speech Therapist - All

Esra Yücel, Gamze Atay - Speech Terapist and ENT - All

Çiğdem Kirazlı - Psycologist - All

Non-clinical and laboratory research

Non-clinical and laboratory team members who are or would like to be involved in clinical research:
Member details: Figen Özgür, Ersoy Konas - PRS - All

Müge Aksu - Orthodontics - All

Maviş Kayıkçı - Speech Therapist - All

Potential laboratory based research activities

Laboratory based research activities interested in being involved in:
Laboratory genetics/genomics research: Yes
Animal models research: Yes