No. of Cases Seen in a Year

  • Total Referrals: 35
  • Unilateral (one sided) cleft lip only: 8
  • Bilateral (Two sided) cleft lip only: 3
  • Bilateral cleft lip and palate: 3
  • Cleft palate only: 18
  • Pierre Robin Sequence: 4

Treatment Funded by State for National Residents

  • Surgery costs: All
  • Speech and Language Therapy costs: All
  • Orthodontic costs: All

Primary surgical protocol


Cleft Lip Repair:

  • Timing: 6 months
  • Type of operation: Tenisson

Bilateral Cleft Lip Repair:

  • Timing: 6 months
  • Type of operation: Manchester

Cleft Palate Repair:

  • Stages: Two stage
  • 1st Stage Timing: 12 months
  • 1st Stage Type of operation: Intravelar veloplasty
  • 2nd Stage Timing: 30 months
  • 2nd Stage Type of operation: Hard palate & gingioperioplasty of alveolus. In isolated cleft palate 30 months modified Von Langenbeck

Record collection protocol


Are records routinely collected at specific ages? Yes

Does this conform to WHO recommendations for different cleft types? Yes

Research

Want to particpate in research? yes

Participation in inter-centre studies?

Current Research

Type(s) of software used: Excel, Word,
Original program for registration, surgery planning, follow up
Participation in inter-centre studies: Yes
Details of studies: A six-center study on dental casts:
Cleft Palate Craniofac J, 2011, doi: 10.159710-190.
Comparison Ljubljana – Graz :
J Craniomaxillofac Surg 2007; 35:343-349
J Craniomaxillofac Surg 2011; 39:469-74
Comparison Ljubljana – Plovdiv:
will be presented at 21st European Congress of Craniomaxillofacial Surgery
Published research papers: Yes
Details of publications: – Cleft Palate Craniofac J 1999; 36: 515-521.
– Cleft Palate Craniofac J 2000; 37:26-32
– J Craniomaxillofacial Surg 2000; 28: 201-203.
– Cleft Palate Craniofac J 2001; 38: 164-170.
– J Laryngol Otol 2006; 120: 276-281.
– Plast Reconstr Surg 2007; 120: 738-745.
– J Craniomaxillofac Surg 2007; 35:343-349
– J Craniomaxillofac Surg 2011; 39:469-74
– Cleft Palate Craniofac J 2011, doi: 10.159710-146.
– Cleft Palate Craniofac J, 2011, doi: 10.159710-190.
Research grant funding received: Yes
Details of funding: Slovene Research Agency
Willing to share Powerpoint presentations: Yes

Ho?evar-Boltežar I, Jarc A, Koželj V. Ear, nose and voice problems in children with orofacial clefts. J Laryngol Otol 2006; 120(4):276-81.
Zemann W, Mossbock R, Karcher H, Koželj V. Sagittal growth of the facial skeleton of 6-year-old children with a complete unilateral cleft of lip, alveolus and palate treated with two different protocols. J Craniomaxillofac Surg 2007; 35(8):343-9.
Koželj V. Experience with presurgical nasal molding in infants with cleft lip and nose deformity. Plast Reconstr Surg 2007; 120(3):738-45.
Zemann W, Karcher H, Drevenšek M, Koželj V Sagittal maxillary growth in children with unilateral cleft of the lip, alveolus and palate at the age of 10 years : an intercentre comparison. J Craniomaxillofac Surg 2011; 39(7):469-74.
Eberlinc A, Koželj V. Incidence of residual oronasal fistulas : a 20-year experience. Cleft Palate Craniofac J, 2011, doi: 10.1597/10-146.
Koželj V et al. Palate dimensions in six-year-old children with unilateral cleft lip and palate; a six-center study on dental casts. Cleft Palate Craniofac J, 2011, doi: 10.1597/10-190.


Clinical research activities interested in being involved in:

Randomised clinical trials: Yes
Inter-centre comparison of outcome: Yes
Prospective study: Yes
DNA collection: Yes




Clinical research

Clinical team members who are or would like to be involved in clinical research:
Member details: Vesna Koželj - Surgery - Inter-centre

Andreja Eberlinc - Surgery - Cohort studies

Martina Drevenšek - Orthodontics -

Irena Ho?evar - ENT

Non-clinical and laboratory research

Non-clinical and laboratory team members who are or would like to be involved in clinical research:
Member details: Vita Dolžan - Molecular genetics

EU Biobank

Stored CLP DNA samples available for use in future studies:
Number for CP: We have 100 Slovene duo
mother child

Potential laboratory based research activities

Laboratory based research activities interested in being involved in:
Laboratory genetics/genomics research: Yes
Animal models research: Yes