No. of Cases Seen in a Year

  • Total Referrals: 40
  • Unilateral cleft lip and palate: 20
  • Bilateral cleft lip and palate: 5
  • Cleft palate only: 15
  • Pierre Robin Sequence: 3

Treatment Funded by State for National Residents

  • Surgery costs: All
  • Speech and Language Therapy costs: Part
  • Orthodontic costs: Part

Comment on the service provision:

Orthodontics and speech therapy are sometimes performed in private clinics.

Primary surgical protocol


Cleft Lip Repair:

  • Timing: 6 months
  • Type of operation: Millard

Bilateral Cleft Lip Repair:

  • Timing: 6 monthd
  • Type of operation: Millard

Cleft Palate Repair:

  • Stages: Two stage
  • 1st Stage Timing: 6-12 months
  • 1st Stage Type of operation: Soft palate repair - Von Langenbeck
  • 2nd Stage Timing: 3 years
  • 2nd Stage Type of operation: Hard palate repair - Veau-Wardill-Kilner

Record collection protocol


Are records routinely collected at specific ages? Yes

Does this conform to WHO recommendations for different cleft types? No

At 3 years old - speech evaluation
At 5-6 years old – clinical evaluation if secondary procedures needed
At 14-15 years old – clinical evaluation if secondary procedures needed

Research

Want to particpate in research? yes

Participation in inter-centre studies?

Current Research

Type(s) of software used: Access database since 2001
Photos
Palatal molds for some children
Participation in other collaborations (projects): Yes
Details of projects: Smile Train
2008 – EBOPRAS (European Board of Plastic, Reconstructive and Aesthetic Surgery) accreditation for cleft lip and palate treatment
Published research papers: Yes
Details of publications: General principles in treating bilateral cleft lip, The Annals of Plastic Surgery and Reconstructive Microsurgery, 32004
Operative techniques for primary surgical treatment of unilateral cleft lip, The Annals of Plastic Surgery and Reconstructive Microsurgery, 32004
Therapeutic protocol in bilateral cleft lip, The Annals of Plastic Surgery and Reconstructive Microsurgery, 32005
Therapeutic protocol in unilateral cleft lip, The Annals of Plastic Surgery and Reconstructive Microsurgery, 32005
A treatment concept for the cleft palate, The Annals of Plastic Surgery and Reconstructive Microsurgery, 32005
An overview to congenital facial malformations, The Annals of Plastic Surgery and Reconstructive Microsurgery, 32006
Surgical alternatives in primary treatment of cleft lip and palate, The Annals of Plastic Surgery and Reconstructive Microsurgery, 32008
Research grant funding received: Yes
Willing to share Powerpoint presentations: Yes

Clinical research activities interested in being involved in:

Randomised clinical trials: Yes
Inter-centre comparison of outcome: Yes
Prospective study: Yes
DNA collection: Yes





Clinical research

Clinical team members who are or would like to be involved in clinical research:
Member details: Prof. Dr. Dan Mircea Enescu - Plastic surgery - clinical trial

Dr. Simona Stoicescu - Plastic surgery - clinical trial

Dr. Raluca Alexandru - Plastic surgery - clinical trial

Dr. Dan Ionita - Plastic surgery - clinical trial

Dr. Raluca Bulea - Plastic surgery - clinical trial

EU Biobank

Stored CLP DNA samples available for use in future studies:
Number for CP: no
Number for CLP: no
Other CFA: no

Potential laboratory based research activities

Laboratory based research activities interested in being involved in:
Laboratory genetics/genomics research: Yes